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Query: sp|P61221|ABCE1_HUMAN ATP-binding cassette sub-family E member 1 OS=Homo sapiens GN=ABCE1 PE=1 SV=1, from H.sapiens

Results of FFAS03 search in PfamA26U
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDDLast
1 -24.700PF00005.22; YTFR_ECOLI/49-174; ABC transporter  ali follow..  15  1....................................................................................................................STLIKALTGVYHADRGTIWLEGQAISPKNTAH--AQQLGIGTVYQE-VNLLPNMSVADNLFIGREPKRFGLLRRKEMEKRATELMASYGFSLDVREPLNRFSVAMQQIVAICRAIDLSAKVLILDEPTA.................................................................................................................................................................................................................................................................................................................................................................. 126
2 -23.000PF09818.4; Q2C6W1_9GAMM/1-438; Predicted ATPase of the ABC class  ali follow..  10  2....................................................................................................................QLLEAKLHKIDRHNYRSYT------SMRGEYHFVDFDFYIDTVQSDPFAP--ASRVRARRAWSLTDLEWLREKSPVYQCAARDFIARFFADLSQQDNAVLIDMPGQVILDRTAVVFDDEGIELVNLPADGRTIIAKRTMNLLTFHLPKMIRRATIAREELKAHCEAAEDQVALRAQLKAHKLLAFV----------------------ADGSILPRLAGNSDLPLPNAVPFTSPDNLSVELEAPYKGKIRGMGIPEGITLIVGGGFHGKSTLLSAIERSVYDHIPGDGREYVVTNYNAAKIRAEDGRCVHNV-----------DLSPYISNLPMGKDTTAFTSQNASGSTSQASWLQESIEAGAEALLIDEDTSASNFMIRTPLVDRIALLRDQHDISVMLVMGGSGDYLDVADTVIQMHNYEAVD......................................................... 408
3 -20.300PF13401.1; B2UJB3_RALPJ/42-210; AAA domain  ali follow..  15  2.................................................................................................................................................................................................................................................................................................................................................................................SQESILLVCGPTGAGKTTLAKFMVENAHSQSHGVIPAIYVQAPASGETKFSWRLFYQRILNQLGDDLDSPKVAYGVDSLSG--RLVRPRGTSGNSLAALRTAVERGLARQVQFMVIDEAAHIFRDSKLEVQLDTLKSLVNECGTQIVLVSYDLYHL.......................................................................... 168
4 -17.100PF13558.1; A3YC50_9GAMM/971-1061; Putative exonuclease SbcCD, C subunit  ali follow..  21  2.........................................................................................................................................................................................NIRDYRKYFVYDVEVTDVTQERYYVSDQMGTGSGGEKQSVAIASSLATAAGLALLDEAFDKLDEENLKNAMDFMGD.................................................................................................................................................................................................................................................................................................................................................. 90
5 -16.000PF13166.1; Q63PW4_BURPS/9-780; AAA domain  ali follow..  11  25......................................................................................................KKMNVIYGRNYSGKTTLSRIIRSLETGSISPRYASPSFSITISGSKNKEIEVEIDKLEDELGSVENKTGLRHSYQEKKKAHADKKKAAQDAQDELDKKIFDKDIKTVQDKKIAPLDDADRSSKVKLLSEVALPDI-LPADLWKRLGDHFNQESQDLEKDLDSVLTKISNEKTRIKNVVTVDRKNFYSANQATFDNLKADLDDAINNHEKSLQSLEDELNARKKDIFTERSTIDVQDNTVSISQKVSLVNELIERNNKTTTSLEEDQKIARNEL---------LSEISQFTIDIDLAGEEKKIKALEDQITKAKDELDAVEAEGKKRVDRVKELRTQLRDEKRGAEQVNLGHFLDQAAYNLSEGECSLVAFCYFLAKKKLIIYIDDPISSLDSNHIFFVFSLIENYITKRYEQLFISTHNLEFLKYLKRLT................................................................... 633
6 -15.400PF10443.4; Q5B2U3_EMENI/373-791; RNA12 protein  ali follow..  11  3........................................................................................NDIEQLNSWLTESAETFIVIHGPRGSGKRELVLDRTLKDNKYKLIIDCKQIQDAKGDTAKIARAASQVGYRPVFSWMNSISSFIDLAAQGMIGTKAGFSETLDAQLSNIWQNTAVALKSITLEHRKKTDPDAQLSDEEYLEAHPEVRPVVVIDNYLHNNPEATSVKITEWAAGLATGNIHVIFLTTDVSFAKPLSKALPNTVFRTISLGDCS-----LEVGRKFVLNHLEHEARNKNKDTRHEEDLAELD----------------------------------SCIGVLG----GRLTDLEFMAHRIEAGETLKMFILNPESESQKWTHQQAWHLIKTLARSKDGSVPYNHVIQSDLNSQALRELEQAELISIVNGSPERVRAGRPVYQAVFKRLTENKSSRLD-------MEVLSQLISKENKSIGKYEEELLLLGKL....................................................................... 419
7 -14.500PF13175.1; A9A6W0_METM6/4-391; AAA ATPase domain  ali follow..  9  4.....................................................................FRIKNY--------------KSIKDSGDVYLSPDNITILAGMNESGKTSVLEALEDFNVGKTVRESAKPICGNKLNVEELEKISKDISNIYLSNDFSKNIELEVKKVGSTYFLENNDIYSEDYNIGIINTLVEIENEINTLSKNIDVIFPTEFNSVEEFRKIMDQKIKDGKSKITDDFNEKIKTQLNALFDEAQKYTLYFLDIDKTLNYIENVVKKEYIPNFIIFKTYKDSKIPNIIPFANLETDEFIKDLQKVSNLDINLIKSTDRQRKKNHHGAININLQEDYSKYWTQSESNLEITWDNNNVEFWVKEDN------------------------------------------------------------------------TSYTPEQRSKGKQWHLAFYIRITGKNNILLIDEPGLFLHAQAQEDIINKLEDASKTMS--IIYTTHSPYLL.......................................................................... 388
8 -14.200PF07088.6; GVPD1_HALSA/23-536; GvpD gas vesicle protein  ali follow..  9  1.............................................................................................LSQFFMGDAGETLLINGAPGTGKTLFIRGLDVLDRDSDV-----------------------LYVSTRVDQETVHEMYFADHSSLDTTAILDLFQDPFELPLDVDVPFEKLDLDSLLEWIQEINAATTQLTIAFDSWELIYEYLAVRHDDPPDI----KTVTNQLAVLAREENIRLMLVTEAPSSLEYIVDGVVTLQVKEDDRGRTRRDLRLDKLRGVRIGNRLQPFTLADGQFQVPVELLTIQTGTGNGTWDPLANSKAKFSTGIRDLDRISGGYNRGSVVHLDLGPDLSRDAWSVLTLPTIRNFLSQEMGVAVVPPREGSPGLLHNDLNTVLSSQVFDTYCHVFETYAGPSDSADRYDQPDS-TESFSEMATTTPPDDAPTATHETDGADDGSRSTDGVTGSDQPHPIDEDFESPIEGGQLYMAYVEQVREESEDPLLHVISMDTAQEAFETRLGDFANYVALHNDLTLLITKQGTELRTRADRVADMHFRLERSGDAIILY.. 486
9 -13.100PF13481.1; Q7U700_SYNPX/79-275; AAA domain  ali follow..  13  32................................................................................................................................................................................................................................................................................................................................................................................IAARTLTLVVALQKVGKSAVVCNILGELAKGRGEFLERFSLAPPCPKVIIVGTDQPLADWREVMVPNGLMIRTDLDNYRVCDVRLYTREHGLHLDEAGIEKIT-ADCEQNPWAVLVLDAFLSLIDSDAAVQPLQNLLESIAPFNITTVLLHH............................................................................... 191
10 -11.100PF03266.10; NTPTH_METS5/13-164; NTPase  ali follow..  15  2.........................................................................................................LFITGRPGVGKTTLIKGL--------------------------------VSELRELKIAGFYTEEVRERGERTGFLFVVIGDGSCPLASTKPIGKERVGRYFVVD---------SLTLLPQVKQRLEVADLVIMDE-IGPMEKKIG-DLWKLIQGVLSSNKPVVASVH..................................................................................................................................................................................................................................................................................................................................... 127
11 -11.000PF13521.1; A4CIV1_ROBBH/14-173; AAA domain  ali follow..  14  2......................................................................................................................................................................................................................................................................................................................................................................................VVLFGPESTGKTTLARELARHYGPWVPEYAREYLQEKWDRVQQTCAPEDLLPIARGQMRLENIGAREASRLL-------ICDTDLLEYYGGGCDPKLQAAALANDYDLYFLTDIDIPWKPHERAEMFHYFKTALRENNRRFVILSGGRE............................................................................ 158
12 -10.800PF13304.1; B1HP30_LYSSC/55-363; AAA domain  ali follow..  17  1........................................................................................................SAFIFGPNGSGKSNLFTALKVLLDGALYEYEIQYNASIILYERLHKTTHNLKEELFVRRWDGVDYSLFLDEANRLSSHPLIRKLEEEPFKKEVIKLLKIADFSGNETINWTMDSKGTVRMLHLACVMYNKGKTIFIDEFDTAFHVSICEFLMAIMNSKRNTSNQFVVTSHEIELLD............................................................................................................................................................................................................................................................................................................................... 309
13 -10.600PF07931.7; Q98FG2_RHILO/59-238; Chloramphenicol phosphotransferase-like protein  ali follow..  9  1......................................................................................................ARIVLLNGVGSAGKSSIARALQTITAAPF--LHVQMDSFLEMLPDALQDHADGFSYETVRQDGKPAVVIRAGPVGERTLRGMRHAIAA--AGQGNDLIVDDVLCNGELSDCVDLLSAFDFHLVGV------MAPLEVLEAREARRADRLPGLARWQYERVHAGISYDLEVDTSQSTPLECARRIQ........................................................................................................................................................................................................................................................................................................................ 176
14 -10.500PF07652.9; Q32ZD8_9FLAV/1675-1822; Flavivirus DEAD domain  ali follow..  14  1................................................................................................................................................................................................................................................................................................................................................................................FKKKQLIVLDPHPGAGKTRKV------------PEFIRQAVERRLWTLALAPTRVVAAEMAEALNG-----LPVRYLTPAVIQQHTGKEIVDLMCHATFTMRLLSGGRVPNYNMFIMDE--AHFTDPSSIAARGYISTKVDMGEASAVFMT................................................................................ 133
15 -10.500PF06745.8; O29463_ARCFU/20-274; KaiC  ali follow..  12  23..........................................................................................................................................................................................................................................................................................................................................................................RKPLGGIPHLAVMNITGVPDTGKSLLAEQFA------------ITQAGSGYRVLYVTVESPANFLYTAMKERSEAMGVDFTKVESNVVVIDASESDELRENPKALMETMAYAIKEKKVTNTIIDSITGLYKEMMARQIVRQFFNFMKKYRQTGIFVSQ--LAVAHIVDGTIVLD............................................................... 199
16 -10.500PF13191.1; B3QEJ6_RHOPT/306-495; AAA ATPase domain  ali follow..  13  15............................................................................................AYHRAASTGTTEWVLISGYSGAGKSSVVSELRKSLAPTNGWF---------IAGKFDQYKRDIPFATLAQAFRSLVRQILGLDCGELDQWRTALQEAVGEHGELMVNLVPDLALVIGEQLPLPDLPPQESKRFLAAIARAEHPLVLFLDD-LQWLDKATSEFLVRLAQNIDTRHLLLV......................................................................................................................................................................................................................................................................................................................................... 190
17 -10.200PF05707.7; Q38198_9VIRU/7-180; Zonular occludens toxin (Zot)  ali follow..  11  1....................................................................................................................................................................................................................................................................................................................................................................................SISLLTGLPGSGKSLRI-------------------------------------------------IQAIRYLMDKGAHVYVCNIDGISVPGTTPWADPHKWQDLPAGSILFVDEAQHFFPARRGGDPVETIKAMSRHDGVRLVLATQQPNYLDTYLRGLV.................................................................. 114
18 -9.820PF11398.3; Q6D3T4_ERWCT/1-377; Protein of unknown function (DUF2813 topsan)  ali follow..  12  1.....................................................................MHLESIEIL-----------GFRGINRLSLTLDENNV-LIGENAWGKSSLLDALSLLLAPTLPLYHFDMQDLAQQFEQLIRELVQNPQKLTDKELRQGLVAMQ-QLLEHYFSEQNATGNDRRHHRHARTHNGKSWRSLDNINRLIADPNSRSSRIILLELFSTLARPLLLIEDPETRLHPIMLSVAWGLLTQLPLQ---KVTTTNSGELLSLVMEQVCRLV..................................................................................................................................................................................................................................................................................................................... 342
19 -9.720PF04068.10; A3FQC8_CRYPV/19-50; Possible Fer4-like domain in RNase L inhibitor, RLI  ali follow..  77  2......RIAIVEADRCKPKNCRQECKSFCPVVRTGKL.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 32
20 -9.600PF00485.13; KPPR_SYNY3/10-192; Phosphoribulokinase / Uridine kinase family  ali follow..  13  1.....................................................................................................................................................................................................................................................................................................................................................................................LIGVAGDSGCGKSTFLRRLTDLFGEEFMTVICLDDYHSLDRQGRKAAGVTALD-------PRANNFDLMYEQIKTLKSGQSIMKPIYNHETGLLDP----PEKVEPNKVVVIEDFGVYLDISEEVKINWKIQRDMAERGHTYEDILASINARKPDFTAYI.................................................................. 163
21 -9.530PF13555.1; Q0A6A1_ALHEH/19-80; P-loop containing region of AAA domain  ali follow..  25  17................................................................................................WSLQPGGDNSLLTGDIGSGKSTLVDAITTLLVPAQ.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 51
22 -9.510PF13207.1; B2WP20_PYRTR/6-173; AAA domain  ali follow..  7  1.....................................................................................................................................................................................................................................................................................................................................................................................IIGLYGISGSGKSYLLNHVKTEIALQA-------------RFAFYDGSEVLAHVTPGGLDSFKLLDAAAKQSRIEAALALITQTCLDRVAGHPGVVVAVEKDWQTYTHIVYLDTAPGVIDLTRHRVVVDELRAICREKGIIFTTLREK.............................................................................. 165
23 -9.500PF10649.4; A6X300_OCHA4/7-165; Protein of unknown function (DUF2478 topsan)  ali follow..  10  1.....................................................................................................................................................................................................................................................................................................................................................................................LAAILAAKDVPVDQLLAGVAHRARQAG----LRVAGFLQHRESNTDECCRDIEIEHIGTGVTQIISQSLGSGSKGCRLDP---------AALADVAGSLLAELDSGADMLILNR-FGKGETEGHGFRSIIEIAYARQIPVLTVVRETYVEGWNDFAGDCGVL................................................................ 148
24 -9.450PF01695.12; Y4IQ_RHISN/60-238; IstB-like ATP binding protein  ali follow..  14  37........................................................................................................................................................................................................................................................................................................................................................................AIAAGDSWLAKGANILLFGPPGGGKSHLAAAI-GLALIENGWRVLFTR---------------------------------TTDLVQKLQVARRELQLESAIA-------------LDKFDLLILDD--VTKDQAETSVLFELISARYER--RSIMITANDPAMTLAAVDRLV.................................................................. 173
25 -9.330PF13671.1; B2JHT3_BURP8/20-178; AAA domain  ali follow..  18  1.....................................................................................................................................................................................................................................................................................................................................................................................LVFICGHAGTGKTTLAKRLIGPLMKATGEACCLLDKDTLYGVYSAA------AIGALTGDPNDRDSPLFLQHFRDPEYRGLFDTAAENLRLGIG---------------VIAVGPLSR-EVRERRLFDHVWLGVPKDAKISVVWVSTSEETAREIAAR.................................................................... 137
26 -9.200PF04665.7; A7XCQ5_9POXV/6-246; Poxvirus A32 protein  ali follow..  10  16......................................................................................................................................................................................................................................................................................................................................................................................LALVGGSGSGKTAYLLSL-----------------------FNTLVEQYRHIFLFTPVYNSEYDSYIWPDHVNKVSTSEELDYALITTKQKIEKYVKNRGNKNAEMFLLILDD----GDKQIKSSCLLDFLNHGRHLNTSIILLCQTYKNGRTSITHFCCCNVSDSDIENMLRSMSITGSKKDLLKCVSLLRAISVHKRRVIIIEDSVFSEGEQRVCYDTAD... 215
27 -9.120PF05621.6; Q48383_KLEAE/1-302; Bacterial TniB protein  ali follow..  11  60..................................................................................................................................................................................................................................................................................................................................................................................RMPNLLLVGPTNNGKSMIVEKFRRTHPASSDADQEHIPV------------------LVVQMPSEPSVIRFYVALLAAMGAPLRPRPRLPEME-----QLALALLRKVGVRMLVIDELHNVLAGNSVREFLNLLRFLGNELRIPLVGV................................................................................. 186
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Jaroszewski L, Li W, Godzik A. In search for more accurate alignments in the twilight zone. Protein Sci. 2002 Jul;11(7):1702-13.